|Full Name||superoxide dismutase 2, mitochondrial|
|Product Description||Mouse Monoclonal antibody [GT1433] to SOD2 (superoxide dismutase 2, mitochondrial)|
|Background||This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||MNSOD Antibody, IPOB Antibody, superoxide dismutase 2, mitochondrial Antibody, MVCD6 Antibody|
|Cellular Localization||Mitochondrion matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SOD2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Pig, Chicken, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (88%), Xenopus laevis (86%), Pig (94%), Chicken (91%), Sheep (94%), Rhesus Monkey (98%), Chimpanzee (100%), Bovine (94%)|