Full Name | SON DNA binding protein |
Background | The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq] |
Synonyms | DBP-5 Antibody , SON3 Antibody , BASS1 Antibody , SON DNA binding protein Antibody , C21orf50 Antibody , NREBP Antibody |
Cellular Localization | Nucleus speckle |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human SON. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Conjugation | Unconjugated |