|Applications||ICC/IF, IHC-Fr, IHC-P, IP, WB|
Not tested in other applications.
| IHC (Frozen sections)||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls|| MCF-7|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||SRY (sex determining region Y)-box 3|
|Product Description||Rabbit Polyclonal antibody to SOX3 (SRY (sex determining region Y)-box 3)|
|Background||This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. [provided by RefSeq]|
|Synonyms||GHDX Antibody, SOXB Antibody, SRY (sex determining region Y)-box 3 Antibody, MRGH Antibody, PHP Antibody, PHPX Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human SOX3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|