|Full Name||sperm autoantigenic protein 17|
|Product Description||Rabbit polyclonal antibody to SPA17 (sperm autoantigenic protein 17)|
|Background||This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.|
|Synonyms||CT22 antibody, SP17 antibody, SP17-1 antibody, SPA17 antibody, sperm surface protein Sp17 antibody, sperm protein 17 antibody, cancer/testis antigen 22 antibody, sperm autoantigenic protein 17 antibody|
|Cellular Localization||Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPA17. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rhesus Monkey (97%), Bovine (80%)|