|Full Name||sperm associated antigen 8|
|Product Description||Rabbit Polyclonal antibody to SPAG8 (sperm associated antigen 8)|
|Background||The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq]|
|Synonyms||BS-84 antibody, HSD-1 antibody, MGC26201 antibody, SMP1 antibody, SPAG3 antibody, hSMP-1 antibody, SPAG8 antibody, sperm membrane protein 1 antibody, sperm membrane protein BS-84 antibody, sperm-associated antigen 8 antibody, sperm associated antigen 8 antibody|
|Cellular Localization||Acrosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPAG8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Mouse, Rat|
|Predict Reactivity Note||Bovine (80%), Mouse (80%), Rat (80%)|