|Full Name||spastic paraplegia 7 (pure and complicated autosomal recessive)|
|Product Description||Rabbit Polyclonal antibody to SPG7 (spastic paraplegia 7 (pure and complicated autosomal recessive))|
|Background||This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]|
|Synonyms||CAR antibody, CMAR antibody, FLJ37308 antibody, MGC126331 antibody, MGC126332 antibody, PGN antibody, SPG5C antibody, SPG7 antibody, paraplegin antibody, cell adhesion regulator antibody, "paraplegin, isoform 1 antibody", cell matrix adhesion regulator antibody, spastic paraplegia 7 protein antibody, spastic paraplegia 7 (pure and complicated autosomal recessive) antibody|
|Cellular Localization||Mitochondrion membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPG7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (85%), Bovine (90%)|