|Full Name||speckle-type POZ protein|
|Product Description||Rabbit Polyclonal antibody to SPOP (speckle-type POZ protein)|
|Background||This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq]|
|Synonyms||TEF2 antibody, SPOP antibody, roadkill homolog 1 antibody, speckle-type POZ protein antibody, HIB homolog 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPOP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (99%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)|