|Full Name||sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)|
|Product Description||Rabbit Polyclonal antibody to SPR (sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase))|
|Background||This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq]|
|Synonyms||SDR38C1 antibody, SPR antibody, sepiapterin reductase antibody, "short chain dehydrogenase/reductase family 38C, member 1 antibody", "sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPR. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (97%), Bovine (82%)|