SPR antibody [N2C3]
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||28 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)|
|Product Description||Rabbit Polyclonal antibody to SPR (sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase))|
|Background||This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq]|
|Synonyms||SDR38C1 antibody, SPR antibody, sepiapterin reductase antibody, "short chain dehydrogenase/reductase family 38C, member 1 antibody", "sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPR. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rabbit (86%), Rhesus Monkey (97%), Bovine (82%)|