|Full Name||sprouty homolog 4 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to SPRY4 (sprouty homolog 4 (Drosophila))|
|Background||SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM]|
|Synonyms||SPRY4 antibody, protein sprouty homolog 4 antibody, spry-4 antibody, sprouty homolog 4 (Drosophila) antibody|
|Cellular Localization||Cytoplasm , Cell projection , ruffle membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPRY4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Sheep, Bovine|
|Predict Reactivity Note||Rat (94%), Sheep (94%), Bovine (95%)|