|Full Name||spectrin, beta, non-erythrocytic 1|
|Product Description||Rabbit Polyclonal antibody to SPTBN1 (spectrin, beta, non-erythrocytic 1)|
|Background||Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||SPTB2 Antibody , betaSpII Antibody , spectrin, beta, non-erythrocytic 1 Antibody , ELF Antibody|
|Cellular Localization||Cytoplasm , cytoskeleton (By similarity) , myofibril , sarcomere , M-band (By similarity) , Isoform 2: Cell membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SPTBN1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (93%), Chicken (94%), Rhesus Monkey (100%), Bovine (96%)|