SQSTM1 antibody [GT239]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||HepG2 , A549 , H1299 , Huh-7 (untreated) , Huh-7 (3 µM Thapsigargin treatment for 12 hr) , Huh-7 (3 µM Thapsigargin treatment for 24 hr) , HepG2 (3 µM Thapsigargin treatment for 12 hr) , HepG2 (3 µM Thapsigargin treatment for 24 hr) , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||sequestosome 1|
|Product Description||Mouse Monoclonal antibody to SQSTM1 |
|Background||This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]|
|Synonyms||p62 Antibody, A170 Antibody, OSIL Antibody, sequestosome 1 Antibody, p62B Antibody, p60 Antibody, ZIP3 Antibody, PDB3 Antibody|
|Cellular Localization||Cytoplasm , Late endosome , Nucleus |
|Species Reactivity||Human, Rat|