SCAP antibody [C2C3], C-term
Not tested in other applications.
| IHC (Formalin-fixed paraffin-embedded sections)||Assay-dependent dilution
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||140 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||SREBF chaperone|
|Product Description||Rabbit polyclonal antibody to SCAP (SREBF chaperone)|
|Background||This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq]|
|Synonyms||KIAA0199 antibody, SCAP antibody, SREBP cleavage-activating protein antibody, sterol regulatory element-binding protein cleavage-activating protein antibody, sterol regulatory element binding protein cleavage-activating protein antibody, SREBF chaperone antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) , Golgi apparatus membrane; Multi-pass membrane protein (By similarity) , Cytoplasmic vesicle , COPII-coated vesicle membrane; Multi-pass membrane protein (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human SREBF chaperone protein. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Bovine|
|Predict Reactivity Note||Rat (95%), Pig (97%), Bovine (96%)|