|Full Name||serum response factor (c-fos serum response element-binding transcription factor)|
|Product Description||Rabbit Polyclonal antibody to SRF (serum response factor (c-fos serum response element-binding transcription factor))|
|Background||This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq]|
|Synonyms||MCM1 antibody, SRF antibody, serum response factor antibody, serum response factor (c-fos serum response element-binding transcription factor) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SRF. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (96%), Bovine (97%)|