SSA1 antibody [C1C3]
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||54 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tripartite motif containing 21|
|Product Description||Rabbit Polyclonal antibody to SSA1 (tripartite motif-containing 21)|
|Background||This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq]|
|Synonyms||RNF81 antibody, RO52 antibody, SSA antibody, SSA1 antibody, TRIM21 antibody, 52 kDa ribonucleoprotein autoantigen Ro/SS-A antibody, sjoegren syndrome type A antigen antibody, 52 kDa Ro protein antibody, RING finger protein 81 antibody, Sicca syndrome antigen A antibody, tripartite motif-containing protein 21 antibody, SS-A antibody, "Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro) antibody", ro(SS-A) antibody, E3 ubiquitin-protein ligase TRIM21 antibody, tripartite motif-containing 21 antibody, tripartite motif containing 21 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SSA1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Cat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Cat (86%), Pig (81%), Rhesus Monkey (99%), Bovine (82%)|