|Full Name||Sjogren syndrome antigen B (autoantigen La)|
|Product Description||Rabbit Polyclonal antibody to SSB (Sjogren syndrome antigen B (autoantigen La))|
|Background||La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]|
|Synonyms||LARP3 antibody, La antibody, SSB antibody, SS-B/La protein antibody, sjoegren syndrome type B antigen antibody, lupus La protein antibody, la autoantigen antibody, autoantigen La antibody, lupus La antigen antibody, "La ribonucleoprotein domain family, member 3 antibody", SS-B antibody, Sjogren syndrome antigen B (autoantigen La) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SSB. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (99%), Bovine (95%)|