|Full Name||suppression of tumorigenicity 14 (colon carcinoma)|
|Product Description||Rabbit Polyclonal antibody to ST14 (suppression of tumorigenicity 14 (colon carcinoma))|
|Background||The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq]|
|Synonyms||HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, ST14 antibody, serine protease 14 antibody, "suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) antibody", tumor associated differentially expressed gene 15 protein antibody, membrane-type serine protease 1 antibody, serine protease TADG-15 antibody, suppressor of tumorigenicity 14 protein antibody, prostamin antibody, tumor-associated differentially-expressed gene 15 protein antibody, suppression of tumorigenicity 14 (colon carcinoma) antibody|
|Cellular Localization||Membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ST14. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (99%)|