|Full Name||ST3 beta-galactoside alpha-2,3-sialyltransferase 5|
|Product Description||Rabbit Polyclonal antibody to ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)|
|Background||Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||SATI antibody, SIAT9 antibody, SIATGM3S antibody, ST3GalV antibody, ST3GAL5 antibody, "sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase, GM3 synthase) antibody", "alpha 2,3-sialyltransferase V antibody", GM3 synthase antibody, "lactosylceramide alpha-2,3-sialyltransferase antibody", ST3Gal V antibody, "CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase antibody", ganglioside GM3 synthase antibody, "ST3 beta-galactoside alpha-2,3-sialyltransferase 5 antibody"|
|Cellular Localization||Golgi apparatus membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ST3GAL5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (90%), Sheep (94%), Rhesus Monkey (98%), Chimpanzee (98%), Bovine (94%)|