|Full Name||STAM binding protein|
|Product Description||Rabbit Polyclonal antibody to STAMBP (STAM binding protein)|
|Background||Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq]|
|Synonyms||AMSH antibody, MGC126516 antibody, MGC126518 antibody, STAMBP antibody, associated molecule with the SH3 domain of STAM antibody, STAM-binding protein antibody, endosome-associated ubiquitin isopeptidase antibody, STAM binding protein antibody|
|Cellular Localization||Nucleus , Membrane; Peripheral membrane protein , Cytoplasm , Early endosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human STAMBP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (83%), Rhesus Monkey (98%), Bovine (88%)|