|Full Name||signal transducer and activator of transcription 1, 91kDa|
|Product Description||Rabbit Polyclonal antibody to STAT1 (signal transducer and activator of transcription 1, 91kDa)|
|Background||The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]|
|Synonyms||DKFZp686B04100 antibody, ISGF-3 antibody, STAT91 antibody, STAT1 antibody, signal transducer and activator of transcription 1-alpha/beta antibody, transcription factor ISGF-3 components p91/p84 antibody, signal transducer and activator of transcription-1 antibody, "signal transducer and activator of transcription 1, 91kDa antibody"|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human STAT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (95%), Xenopus laevis (85%), Pig (97%), Chicken (90%), Sheep (98%), Rhesus Monkey (99%), Bovine (98%)|