STK24antibody [N2C1], Internal
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||49 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , Raji , rat brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||serine/threonine kinase 24|
|Product Description||Rabbit polyclonal antibody to STK24 (serine/threonine kinase 24 (STE20 homolog, yeast))|
|Background||The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM]|
|Synonyms||MST3 antibody, MST3B antibody, STE20 antibody, STK3 antibody, STK24 antibody, sterile 20-like kinase 3 antibody, serine/threonine-protein kinase 24 antibody, STE20-like kinase 3 antibody, "serine/threonine kinase 24 (STE20 homolog, yeast) antibody", mammalian STE20-like protein kinase 3 antibody, STE20-like kinase MST3 antibody, serine/threonine kinase 24 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human STK24. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)|