|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||56 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||serine/threonine kinase 4|
|Product Description||Rabbit Polyclonal antibody to MST1 (serine/threonine kinase 4)|
|Background||The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]|
|Synonyms||DKFZp686A2068 antibody, KRS2 antibody, MST1 antibody, YSK3 antibody, STK4 antibody, mammalian sterile 20-like 1 antibody, kinase responsive to stress 2 antibody, serine/threonine-protein kinase Krs-2 antibody, MST-1 antibody, "dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)) antibody", STE20-like kinase MST1 antibody, mammalian STE20-like protein kinase 1 antibody, serine/threonine-protein kinase 4 antibody, serine/threonine kinase 4 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MST1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|