|Full Name||succinate-CoA ligase, alpha subunit|
|Product Description||Rabbit Polyclonal antibody to SUCLG1 (succinate-CoA ligase, alpha subunit)|
|Background||This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq]|
|Synonyms||FLJ21114 antibody, FLJ43513 antibody, GALPHA antibody, MTDPS9 antibody, SUCLA1 antibody, SUCLG1 antibody, succinyl-CoA synthetase subunit alpha antibody, succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial antibody, succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial antibody, SCS-alpha antibody, succinate-CoA ligase, alpha subunit antibody|
|Cellular Localization||Mitochondrion |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:26991003)|
|Immunogen||Full length human SUCLG1 Recombinant protein.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Chicken, Bovine|
|Predict Reactivity Note||Zebrafish (85%), Pig (88%), Chicken (81%), Bovine (90%)|