|Full Name||surfeit 1|
|Product Description||Rabbit polyclonal antibody to SURF1 (surfeit 1)|
|Background||This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq]|
|Synonyms||SURF1 antibody, surfeit locus protein 1 antibody, surfeit 1 antibody|
|Cellular Localization||Mitochondrion inner membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SURF1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (84%), Rat (82%)|