SUV39H1 antibody [N3C3]
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
| Immunoprecipitation||Assay-dependent dilution
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||48 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , H1299 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||suppressor of variegation 3-9 homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to SUV39H1 (suppressor of variegation 3-9 homolog 1 (Drosophila))|
|Background||This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]|
|Synonyms||KMT1A antibody, MG44 antibody, SUV39H antibody, SUV39H1 antibody, H3-K9-HMTase 1 antibody, histone H3-K9 methyltransferase 1 antibody, histone-lysine N-methyltransferase SUV39H1 antibody, lysine N-methyltransferase 1A antibody, position-effect variegation 3-9 homolog antibody, Su(var)3-9 homolog 1 antibody, "histone-lysine N-methyltransferase, H3 lysine-9 specific 1 antibody", suppressor of variegation 3-9 homolog 1 (Drosophila) antibody|
|Cellular Localization||Nucleus , Centromere |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SUV39H1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Monkey|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (98%), Rhesus Monkey (100%), Bovine (100%)|