|Full Name||SWAP switching B-cell complex 70kDa subunit|
|Product Description||Rabbit polyclonal antibody to SWAP70|
|Background||Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.|
|Synonyms||FLJ39540 antibody, KIAA0640 antibody, SWAP-70 antibody, SWAP70 antibody, switch-associated protein 70 antibody, SWAP switching B-cell complex 70kDa subunit antibody|
|Cellular Localization||Cytoplasm , Cell membrane , Nucleus , Cell projection , lamellipodium |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human SWAP70. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Chicken (85%), Rhesus Monkey (99%), Bovine (94%)|