SYK antibody [N2C2], Internal
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||72 kDa (note)
|Positive Controls||A431 , Raji , mouse BMDM , mouse spleen|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||spleen tyrosine kinase|
|Product Description||Rabbit Polyclonal antibody to SYK (spleen tyrosine kinase)|
|Background||This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp313N1010 antibody, FLJ25043 antibody, FLJ37489 antibody, SYK antibody, tyrosine-protein kinase SYK antibody, spleen tyrosine kinase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human SYK. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (89%), Rhesus Monkey (98%), Bovine (80%)|