|Full Name||exocyst complex component 4|
|Product Description||Rabbit Polyclonal antibody to Sec8 (exocyst complex component 4)|
|Background||The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||MGC27170 antibody, REC8 antibody, SEC8 antibody, SEC8L1 antibody, Sec8p antibody, EXOC4 antibody, exocyst complex component Sec8 antibody, SEC8-like 1 antibody, exocyst complex component 4 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Sec8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (92%), Chicken (89%), Bovine (93%)|