|Full Name||serine palmitoyltransferase, long chain base subunit 2|
|Product Description||Rabbit Polyclonal antibody to Serine palmitoyltransferase 2 (serine palmitoyltransferase, long chain base subunit 2)|
|Background||This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||HSN1C antibody, KIAA0526 antibody, LCB2 antibody, LCB2A antibody, NSAN1C antibody, SPT2 antibody, SPTLC2 antibody, serine palmitoyltransferase 2 antibody, "serine palmitoyltransferase, subunit II antibody", LCB 2 antibody, long chain base biosynthesis protein 2a antibody, SPT 2 antibody, serine-palmitoyl-CoA transferase 2 antibody, "serine palmitoyltransferase, long chain base subunit 2 antibody"|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Serine palmitoyltransferase 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (95%), Xenopus laevis (80%), Chicken (84%), Bovine (95%)|