Full Name | SLIT and NTRK-like family, member 5 |
Background | SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. This antibody is predicted to have no cross-reactivity to other Slitrk proteins. |
Synonyms | SLIT and NTRKlike family 5, Slitrk5 (IN1), SLIT and NTRK-like family 5, SLIT and NTRKlike family5, SLIT and NTRK like family 5 |
Specificity | This antibody is predicted to have no cross-reactivity to other Slitrk proteins. |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Slitrk5 antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slitrk5.The immunogen is located within amino acids 310 - 360 of Slitrk5. |
Antigen Species | Human |
Species Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |