|Full Name||ATPase, Na+/K+ transporting, beta 1 polypeptide|
|Product Description||Rabbit Polyclonal antibody to Sodium/Potassium ATPase Beta 1 (ATPase, Na+/K+ transporting, beta 1 polypeptide)|
|Background||The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||ATP1B antibody, MGC1798 antibody, ATP1B1 antibody, Na, K-ATPase beta-1 polypeptide antibody, Beta 1-subunit of Na(+),K(+)-ATPase antibody, sodium/potassium-transporting ATPase subunit beta-1 antibody, sodium/potassium-transporting ATPase beta-1 chain antibody, sodium/potassium-dependent ATPase beta-1 subunit antibody, adenosinetriphosphatase antibody, ATPase, Na+/K+ transporting, beta 1 polypeptide antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Sodium Potassium ATPase Beta 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rabbit, Sheep, Rhesus Monkey, Chimpanzee, Guinea pig|
|Predict Reactivity Note||Dog (90%), Pig (89%), Rabbit (87%), Sheep (91%), Rhesus Monkey (96%), Chimpanzee (99%), Guinea pig (87%)|