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Sorbitol Dehydrogenase antibody

Anti-Sorbitol Dehydrogenase antibody used in IHC (Paraffin sections) (IHC-P). GTX54728
Anti-Sorbitol Dehydrogenase antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54728
Anti-Sorbitol Dehydrogenase antibody used in Western Blot (WB). GTX54728

Cat. No. GTX54728

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Sorbitol Dehydrogenase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human SORD (NP_003095.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sorbitol dehydrogenase , HEL-S-95n , SORD1

Background

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-Sorbitol Dehydrogenase antibody used in IHC (Paraffin sections) (IHC-P). GTX54728

GTX54728 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX54728 Sorbitol Dehydrogenase antibody.
Dilution : 1:25

Anti-Sorbitol Dehydrogenase antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54728

GTX54728 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX54728 Sorbitol Dehydrogenase antibody.
Blue : DAPI

Anti-Sorbitol Dehydrogenase antibody used in Western Blot (WB). GTX54728

GTX54728 WB Image

WB analysis of various sample lysates using GTX54728 Sorbitol Dehydrogenase antibody.
Dilution : 1:500
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399