FDFT1 antibody [N1C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||48 kDa (note)
|Positive Controls||293T , A431 , H1299 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||farnesyl-diphosphate farnesyltransferase 1|
|Product Description||Rabbit polyclonal antibody to FDFT1 (farnesyl-diphosphate farnesyltransferase 1)|
|Background||This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]|
|Synonyms||DGPT antibody, ERG9 antibody, SQS antibody, SS antibody, FDFT1 antibody, presqualene-di-diphosphate synthase antibody, squalene synthetase antibody, squalene synthase antibody, FPP:FPP farnesyltransferase antibody, farnesyl-diphosphate farnesyltransferase 1 antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human FDFT1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (88%), Rat (86%), Pig (91%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (91%)|