StAR antibody [GT868]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||Jurkat , Raji , NCI-H929 , K562 , THP-1 , HL-60 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||steroidogenic acute regulatory protein|
|Product Description||Mouse Monoclonal antibody [GT868] to StAR (steroidogenic acute regulatory protein)|
|Background||The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq]|
|Synonyms||steroidogenic acute regulatory protein Antibody, StARD1 Antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human StAR. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Cat, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (89%), Dog (93%), Cat (89%), Pig (90%), Sheep (86%), Rhesus Monkey (98%), Bovine (87%)|