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1 .GTX85023 STK39 antibody

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STK39 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsELISA, IHC-P, WB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX85023
Package Price Qty
100 μgUSD 329.00
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  • Anti-STK39 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX85023
  • Anti-STK39 antibody used in Western Blot (WB). GTX85023
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  • Datasheet
  • Application Information: STK39 antibody

Catalog Number GTX85023
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Product Name STK39 antibody
See all STK39 products
ApplicationsELISA, IHC-P, WB
Application Note
Suggested dilutionReference
ELISAAssay-dependent dilution  
IHC (Formalin-fixed paraffin-embedded sections)2.5 μg/mL*  
Western Blot (WB)1 - 2 μg/mL*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Positive ControlsHuman Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography

  • Specifications: STK39 antibody

Full Nameserine threonine kinase 39
BackgroundThe serine/threonine kinase Stk39 belongs to the STE20 family, a group of kinases that are known to interact with inflammation-related kinases (such as p38, JNK, NKCC1, PKC-theta, WNK and MLCK), and with transcription factor AP-1. The STE 20 family is involved in diverse biological phenomena, including cell differentiation, cell transformation/ proliferation, cytoskeleton rearrangement, and the regulation of ion transporters. STK39 contains an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain and is abundantly expressed in the brain. STK39 is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled co-transporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Recent studies show that STK39 tend to be a novel candidate gene for autism and hypertension.
SynonymsSerine Threonine Kinase39, SPS1related prolinealaninerich protein kinase, DCHT, SPAK, Serine Threonine Kinase 39, SPS1-related proline-alanine-rich protein kinase, Stk39, STE20
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenStk39 antibody was raised against a 18 amino acid synthetic peptide from near the center of human Stk39.The immunogen is located within amino acids 360 - 410 of Stk39.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: STK39 antibody

Storage BufferPBS with 0.02% sodium azide.
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Lung > Non-small cell
  • Cell Biology > Cytoskeleton
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Signal Transduction > ECM/Cytoskeleton > Cytoskeleton
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STK39 antibody validated data
  • Anti-STK39 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX85023
    • GTX85023 IHC-P Image
      IHC-P analysis of human brain tissue using GTX85023 STK39 antibody.
      Working concentration : 2.5 μg/ml
      Top
  • Anti-STK39 antibody used in Western Blot (WB). GTX85023
    • GTX85023 WB Image
      WB analysis of rat brain tissue lysate using GTX85023 STK39 antibody.
      Working concentration : (A) 1 and (B) 2 μg/ml
      Top
  • Anti-STK39 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX85023
    • GTX85023 IHC-P Image
      IHC-P analysis of human brain tissue using GTX85023 STK39 antibody.
      Working concentration : 2.5 μg/ml
      Top
  • Anti-STK39 antibody used in Western Blot (WB). GTX85023
    • GTX85023 WB Image
      WB analysis of rat brain tissue lysate using GTX85023 STK39 antibody.
      Working concentration : (A) 1 and (B) 2 μg/ml
      Top
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All products are for research use only—Not for use in diagnostic procedures.