|Full Name||suppressor of fused homolog (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Suppressor of Fused (suppressor of fused homolog (Drosophila))|
|Background||SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).[supplied by OMIM]|
|Synonyms||PRO1280 antibody, SUFUH antibody, SUFUXL antibody, SUFU antibody, suppressor of fused homolog antibody, suppressor of fused homolog (Drosophila) antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Suppressor of Fused. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Rat (95%), Xenopus laevis (89%), Chicken (95%), Rhesus Monkey (100%)|