|Full Name||baculoviral IAP repeat containing 5|
|Product Description||Rabbit Polyclonal antibody to Survivin (baculoviral IAP repeat containing 5)|
|Background||Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene.This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq]|
|Synonyms||API4 antibody, EPR-1 antibody, BIRC5 antibody, survivin variant 3 alpha antibody, apoptosis inhibitor survivin antibody, baculoviral IAP repeat-containing protein 5 antibody, apoptosis inhibitor 4 antibody, baculoviral IAP repeat containing 5 antibody|
|Cellular Localization||Cytoplasm , Nucleus , Centromere |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Survivin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (83%)|