|Full Name||synapsin I|
|Product Description||Rabbit Polyclonal antibody to Synapsin I (synapsin I)|
|Background||This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||SYN1b Antibody , SYNI Antibody , SYN1 Antibody , SYN1a Antibody , synapsin I Antibody|
|Cellular Localization||Cell junction , synapse , Golgi apparatus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Synapsin I. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Human (100%), Rat (100%), Xenopus laevis (86%), Pig (99%), Bovine (98%)|