|Full Name||synaptotagmin I|
|Product Description||Rabbit Polyclonal antibody to Synaptotagmin 1 (synaptotagmin I)|
|Background||The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM]|
|Synonyms||DKFZp781D2042 antibody, P65 antibody, SVP65 antibody, SYT antibody, SYT1 antibody, synaptotagmin 1 antibody, synaptotagmin-1 antibody, sytI antibody, synaptotagmin I antibody|
|Cellular Localization||Cytoplasmic vesicle , secretory vesicle , synaptic vesicle membrane; Single-pass membrane protein , chromaffin granule membrane; Single-pass membrane protein , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Synaptotagmin 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Bovine|
|Predict Reactivity Note||Rat (100%), Chicken (97%), Bovine (100%)|