Syntenin 1 antibody [N1], N-term
|Applications||ELISA, ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
| ELISA||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||32 kDa (note)
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||syndecan binding protein (syntenin)|
|Product Description||Rabbit Polyclonal antibody to Syntenin 1 (syndecan binding protein (syntenin))|
|Background||The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||MDA-9 antibody, ST1 antibody, SYCL antibody, TACIP18 antibody, SDCBP antibody, pro-TGF-alpha cytoplasmic domain-interacting protein 18 antibody, syndecan-binding protein 1 antibody, melanoma differentiation associated protein-9 antibody, syntenin-1 antibody, melanoma differentiation-associated protein 9 antibody, scaffold protein Pbp1 antibody, syndecan binding protein (syntenin) antibody|
|Cellular Localization||Cell junction , focal adhesion , adherens junction , Cell membrane; Peripheral membrane protein , Endoplasmic reticulum membrane; Peripheral membrane protein , Nucleus , Melanosome , Cytoplasm , cytosol , cytoskeleton |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Syntenin 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Zebrafish|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|