| Full Name | syndecan binding protein (syntenin) |
| Product Description | Mouse Monoclonal antibody [3D9-G9-H4] to Syntenin 1 |
| Background | The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Synonyms | syndecan binding protein (syntenin) Antibody , SDCBP Antibody , ST1 Antibody , MDA-9 Antibody , SYCL Antibody , TACIP18 Antibody |
| Cellular Localization | Nucleus. Cytoplasm. Mitochondrion. Note: Cytoplasmic during the interphase. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | 3D9-G9-H4 |
| Target | Syntenin 1 |
| Isotype | IgG2b |
| Immunogen | Purified recombinant human Syntenin 1 protein fragments expressed in E.coli. |
| Antigen Species | Human |
| Species Reactivity | Human |