|Full Name||syntrophin, gamma 2|
|Product Description||Rabbit Polyclonal antibody to Syntrophin gamma 2 (syntrophin, gamma 2)|
|Background||This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq]|
|Synonyms||SYN5 Antibody, G2SYN Antibody, SNTG2 Antibody, syntrophin, gamma 2 Antibody|
|Cellular Localization||Cell membrane , sarcolemma; Peripheral membrane protein; Cytoplasmic side , Cytoplasm , cytoskeleton |
|Target||Syntrophin gamma 2|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Syntrophin gamma 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (86%), Rat (86%)|