|Full Name||transcriptional adaptor 3|
|Product Description||Rabbit polyclonal antibody to TADA3L (transcriptional adaptor 3 (NGG1 homolog, yeast)-like)|
|Background||Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]|
|Synonyms||ADA3 antibody, FLJ20221 antibody, FLJ21329 antibody, NGG1 antibody, TADA3L antibody, hADA3 antibody, TADA3 antibody, STAF54 antibody, ADA3-like protein antibody, transcriptional adapter 3 antibody, ADA3 homolog antibody, transcriptional adaptor 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human TADA3L. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (100%)|