|Full Name||TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa|
|Product Description||Rabbit Polyclonal antibody to TAF12|
|Background||Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||TAF2J Antibody , TAFII20 Antibody , TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TAF12. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus Tropicalis, Dog, Chicken, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (96%), Zebrafish (86%), Xenopus Tropicalis (81%), Dog (98%), Chicken (95%), Bovine (99%)|