|Full Name||TRAF family member-associated NFKB activator|
|Product Description||Rabbit Polyclonal antibody to TANK (TRAF family member-associated NFKB activator)|
|Background||The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||I-TRAF Antibody , TRAF2 Antibody , TRAF family member-associated NFKB activator Antibody , ITRAF Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TANK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (95%), Bovine (86%)|