|Full Name||T-box 21|
|Product Description||Rabbit Polyclonal antibody to TBX21 (T-box 21)|
|Background||This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq]|
|Synonyms||T-PET antibody, T-bet antibody, TBET antibody, TBLYM antibody, TBX21 antibody, T-cell-specific T-box transcription factor T-bet antibody, T-box expressed in T cells antibody, transcription factor TBLYM antibody, T-box protein 21 antibody, T-box transcription factor TBX21 antibody, T-box 21 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TBX21. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (97%), Pig (97%), Bovine (94%)|