TC21 antibody [N1C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||23 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||related RAS viral (r-ras) oncogene homolog 2|
|Product Description||Rabbit Polyclonal antibody to TC21 (related RAS viral (r-ras) oncogene homolog 2)|
|Background||This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||TC21 antibody, RRAS2 antibody, teratocarcinoma oncogene antibody, ras-like protein TC21 antibody, ras-related protein R-Ras2 antibody, related RAS viral (r-ras) oncogene homolog 2 antibody|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TC21. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (96%), Xenopus laevis (82%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%)|