|Full Name||transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)|
|Product Description||Rabbit Polyclonal antibody to TCEB1 (transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C))|
|Background||This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]|
|Synonyms||transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) Antibody , SIII Antibody , eloC Antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TCEB1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Cat, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Xenopus laevis (100%), Cat (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|