TDP43 antibody [GT733]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||A431 , HeLa , HepG2 , 293T , TARDBP shRNA-transfected 293T , U87-MG , SK-N-SH , IMR32 , SK-N-AS|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||TAR DNA binding protein|
|Product Description||Mouse Monoclonal antibody [GT733] to TDP43|
|Background||HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]|
|Synonyms||TAR DNA binding protein Antibody, TDP-43 Antibody, ALS10 Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TARDBP. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Zebrafish (83%), Xenopus laevis (83%), Chicken (95%), Bovine (96%)|