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Catalog Number
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GTX30410
(
2
)
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Product Name
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TERT antibody [2C4]
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| Applications | FACS, ICC/IF, IHC, IHC-P, WB, WB-Ag |
| Application Note | For IHC-P: Use at a concentration of 1:40. For WB: Use at a concentration of 1:500 - 1:1,000. Recognizes a band at ~127 kDa, representing hTERT protein. May see an additional background band at ~110 kDa. Optimal dilutions/concentrations should be determined by the researcher. |
| Positive Controls | 293T whole cell lysates ,HeLa whole cell lysates |
| Form Supplied | Liquid |
| Full Name | telomerase reverse transcriptase |
| Product Description | Mouse monoclonal [2C4] to Human telomerase reverse transcriptase (hTERT) |
| Background | Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. |
| Synonyms | EST2, TCS1, TP2, TRT, hEST2 |
| Cellular Localization | Nuclear |
| Specificity | Is specific for hTERT(1). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | 2C4 |
| Target | TERT |
| Isotype | IgM |
| Immunogen | Recombinant full length protein (Human) from insect cells. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |