|Full Name||tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)|
|Product Description||Rabbit Polyclonal antibody to TFPI (tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor))|
|Background||This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq]|
|Synonyms||EPI antibody, LACI antibody, TFI antibody, TFPI1 antibody, TFPI antibody, tissue factor pathway inhibitor antibody, anti-convertin antibody, extrinsic pathway inhibitor antibody, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TFPI. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rhesus Monkey|
|Predict Reactivity Note||Human (100%), Rhesus Monkey (86%)|